#5 Aquie esta el estudio en el que se basa el árticulo del periódico y es con todo el respeto poco valorable.
Risk of female breast cancer and serum concentrations of organochlorine pesticides and polychlorinated biphenyls: a case-control study in Tunisia.
Arrebola JP1, Belhassen H2, Artacho-Cordón F3, Ghali R2, Ghorbel H2, Boussen H4, Perez-Carrascosa FM5, Expósito J5, Hedhili A2, Olea N3.
Author information
Abstract
The aim of this study was to investigate the association between serum concentrations of a group of organochlorine pesticides/polychlorinated biphenyls with xenoestrogenic potential and the risk of breast cancer in a female population from Tunisia. The relationship between serum levels of the pollutants and the risk of cancer was assessed using logistic regression analyses. In the unadjusted models, β-hexachlorocyclohexane (β-HCH), hexachlorobenzene, heptachlor, polychlorinated biphenyl congeners 138, 153, and 180, and p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) were positively associated with breast cancer risk. However, when the models were further adjusted for the selected covariates, only β-HCH and p,p'-DDE remained statistically significant, and heptachlor was borderline significant. In addition, analyses using POP concentration tertiles corroborated a positive dose-response relationship that was significant for p,p'-DDE (p-trend=0.020) and borderline significant for heptachlor (p-trend=0.078). A similar trend was also confirmed for β-HCH, in which concentrations≥limit of detection were positively associated with breast cancer risk (vs. concentrations<limit of detection, OR=3.44, p<0.05). Finally, the relative influence of each chemical in the presence of the others was assessed by entering the three chemicals in a single model with all covariates, and only β-HCH remained positively associated with the risk of cancer (OR:1.18, 95%CI: 1.05-1.34). Our findings suggest a potential association between exposure to at least one organochlorine pesticide and breast cancer risk. However, our results should be interpreted with caution, and further research is warranted to confirm these findings.
Copyright 2015. Published by Elsevier B.V.
"Chemicals — Organochlorines include polychlorinated biphenyls (PCB's), dioxins, and organochlorine pesticides such as dichlorodiphenyltrichloroethane (DDT). These compounds are weak estrogens, highly lipophilic, and capable of persisting in body tissues for years. However, an association with breast cancer has not been demonstrated [163,164].
163
PubMed
TIOrganochlorines and breast cancer risk.
AUCalle EE, Frumkin H, Henley SJ, Savitz DA, Thun MJ
SOCA Cancer J Clin. 2002;52(5):301.
Organochlorines are a diverse group of synthetic chemicals that include polychlorinated biphenyls (PCBs), dioxins, and organochlorine pesticides such as dichlorodiphenyl-trichloroethane (DDT), lindane, and hexachlorobenzene. Although use of DDT and PCBs has been banned in the United States since the 1970s, some organochlorine compounds have accumulated and persisted within the environment. As a result, measurable amounts can still be found in human tissue. Because some organochlorine compounds act as estrogen agonists or antagonists within in vitro and experimental animal systems, a possible association of breast cancer risk with organochlorine exposure has been hypothesized and investigated. Although a few studies support this hypothesis, the vast majority of epidemiological studies do not. While some of these compounds may have other adverse environmental or health effects, organochlorine exposure is not believed to be causally related to breast cancer. Women concerned about possible organochlorine exposure can be reassured that available evidence does not suggest an association between these chemicals and breast cancer.
ADAmerican Cancer Society, Atlanta, GA, USA.
PMID12363327
164
Willett WC, Rockhill B, Hankinson SE, et al. factors in the causation of breast cancer. In: Diseases of the Breast, Harris JR, Lippman ME, Morrow M, Osborne CK (Eds), Lippincott, Williams and Wilkins, Philadelphia 2004. p.255.
#3 He hablado solamente del parkinson, pero si hablamos de cancer tendremos que especificar el pesticida, y de paso el nivel de cancerigeno ¿puede que sea cancerigeno como la cafeina o es cancerigeno como el tabaco?. Por otro lado los daños causados por el mal uso no son aplicables, ¿o acaso voy a hacer campaña porque la lejia es caustica y le meti un trago?
#0 Interesante articulo. Te voto positivo para compensar ;). Tampoco hagas mucho caso, luego la gente se pasa las normas por el forro, como cuando votan negativo comentarios cuando no les gusta tu opinion.
#5 También te pasa por tener el nick igual a la web. Yo cambiaría eso. Hay gente demasiado sensible con el tema. Se permite que publiques de vez en cuando de tu web si además, publicas de otras webs y aportas comentarios a noticias. Bienvenido y muy interesante el artículo.
#5 El problema es que no queda muy ético darse de alta y el primer envio que se realiza sea de tu propio blog. Da la impresión que te has dado de alta para usar Menéame como propaganda.
2015. Published by Elsevier B.V. 
Como dice #3, mejor carpas o Guppys.